CAS RN 1449277-10-4

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MedChemExpress GNE-495 is a potent and selective MAP4K4 inhibitor with an IC50 of 3.7 nM.

Molecular Weight (g/mol)	405.42
Color	Yellow
Physical Form	Solid
Chemical Name or Material	GNE-495
Grade	Research
SMILES	O=C(C1=C2C=CC(C3=CC=CC(F)=C3)=NC2=C(N)N=C1)NC4CN(C(C5CC5)=O)C4
For Use With (Application)	Cancer-Kinase/protease
Percent Purity	98.07%
CAS	1449277-10-4
Solubility Information	DMSO : 2.17 mg/mL (5.35 mM; Need ultrasonic)
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₂H₂₀FN₅O₂
Formula Weight	405.42