CAS RN 1628316-74-4

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MI-136, MedChemExpress

MedChemExpress MI-136 is an inhibitor of the menin-MLL protein-protein interaction (PPI), with an IC50 of 31 nM and a Kd of 23.6 nM. MI-136 shows to block AR signaling and has the potential for the study in castration-resistant tumors.

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Specifications

Molecular Weight (g/mol)	470.51
Color	White
Physical Form	Solid
Chemical Name or Material	MI-136
Grade	Research
SMILES	FC(F)(F)CC(S1)=CC2=C1N=CN=C2NC3CCN(CC4=CC=C(NC(C#N)=C5)C5=C4)CC3
For Use With (Application)	Cancer-programmed cell death
Percent Purity	99.71%
CAS	1628316-74-4
Solubility Information	DMSO : 110 mg/mL (233.79 mM; Need ultrasonic)
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₃H₂₁F₃N₆S
Formula Weight	470.51

CAS RN 1628316-74-4

CAS RN 1628316-74-4

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