CAS RN 1956366-10-1

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Ulixertinib hydrochloride, MedChemExpress

MedChemExpress Ulixertinib hydrochloride (BVD-523 hydrochloride) is a potent, orally active, highly selective, ATP-competitive and reversible covalent inhibitor of ERK1/2 kinases, with an IC50 of <0.3 nM against ERK2. Ulixertinib hydrochloride inhibits the phosphorylated ERK2 (pERK) and downstream kinase RSK (pRSK) in an A375 melanoma cell line.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	469.79
Color	White
Physical Form	Solid
Chemical Name or Material	Ulixertinib hydrochloride
Grade	Research
SMILES	O=C(C1=CC(C2=CC(NC(C)C)=NC=C2Cl)=CN1)N[C@@H](C3=CC=CC(Cl)=C3)CO.[H]Cl
For Use With (Application)	Cancer-Kinase/protease
Percent Purity	99.81%
CAS	1956366-10-1
Solubility Information	DMSO : 100 mg/mL (212.86 mM; Need ultrasonic) ∣H2O : 0.1 mg/mL (0.21 mM; ultrasonic and warming and heat to 80°C)
Synonym	BVD-523 hydrochlorideVRT752271 hydrochloride
Purity Grade Notes	Research
Recommended Storage	4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Shelf Life	4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Molecular Formula	C₂₁H₂₃Cl₃N₄O₂
Formula Weight	469.79

CAS RN 1956366-10-1

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