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CAS RN 778270-11-4

OH2NNNNHOFFF

CAS RN 778270-11-4

IUPAC Name: 3-(6-{[4-(trifluoromethoxy)phenyl]amino}pyrimidin-4-yl)benzamide
Synonyms: 3-(6-{[4-(trifluoromethoxy)phenyl]amino}pyrimidin-4-yl)benzamide
Molecular Weight (g/mol): 374.32
Molecular Formula: C18H13F3N4O2
InChi Key: WEVYNIUIFUYDGI-UHFFFAOYSA-N
SMILES: NC(=O)C1=CC=CC(=C1)C1=CC(NC2=CC=C(OC(F)(F)F)C=C2)=NC=N1
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GNF-2, MedChemExpress

MedChemExpress GNF-2 is a highly selective, allosteric, non-ATP competitive inhibitor of Bcr-Abl. GNF-2 inhibits Ba/F3.p210 proliferation with an IC50 of 138 nM .

ENCOMPASS_PREFERRED
Molecular Weight (g/mol) 374.32
Color White
Physical Form Solid
Chemical Name or Material GNF-2
Grade Research
SMILES O=C(C1=CC=CC(C2=CC(NC3=CC=C(OC(F)(F)F)C=C3)=NC=N2)=C1)N
For Use With (Application) Cancer-Kinase/protease
Percent Purity 98.73%
CAS 778270-11-4
Solubility Information DMSO : ≥ 100 mg/mL (267.15 mM) ∣H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C) (insoluble)
Health Hazard 1 H315∣H319∣H335
Purity Grade Notes Research
Recommended Storage Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula C18H13F3N4O2
Formula Weight 374.32