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2-Mercapto-1-methylimidazole, 98%, Thermo Scientific Chemicals
2-Mercapto-1-methylimidazole, CAS # 60-56-0, also known as methimazole, is a thyroid hormone antagonist used to study the treatment of thyroid disorders.
85.60 EUR - 690.00 EUR
Chemical Identifiers
| CAS | 60-56-0 |
|---|---|
| Molecular Formula | C4H6N2S |
| Molecular Weight (g/mol) | 114.17 |
| MDL Number | MFCD00179321 |
| InChI Key | PMRYVIKBURPHAH-UHFFFAOYSA-N |
| Synonym | methimazole, thiamazole, 2-mercapto-1-methylimidazole, tapazole, mercazolyl, 1-methylimidazole-2-thiol, mercazole, metazolo, methimazol, thiamazol |
| PubChem CID | 1349907 |
| ChEBI | CHEBI:50673 |
| IUPAC Name | 3-methyl-1H-imidazole-2-thione |
| SMILES | CN1C=CNC1=S |
| Product Code | Brand | Quantity | Packaging | Price | Quantity & Availability | ||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Packaging | Price | Quantity & Availability | ||||
|
10275220
|
Thermo Scientific Acros
125500250 |
25 g | Glass bottle |
85.60 EUR
25g |
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|
10041260
|
Thermo Scientific Acros
125501000 |
100 g | Glass bottle |
183.00 EUR
100g |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
|
11986251
|
Thermo Scientific Acros
125505000 |
500 g | Glass Bottle |
690.00 EUR
500g |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
Description
This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
• 2-Mercapto-1-methylimidazole, also known as methimazole, is an antithyroid medication
• Methimazole works by inhibiting the enzyme thyroid peroxidase (TPO), which is responsible for synthesizing the thyroid hormones triiodothyronine (T3) and thyroxine (T4) from the precursor thyroglobulin
Applications
• Methimazole has been used in laboratory settings to model olfactory epithelial degeneration
• May be used to study disruptions in iodide metabolism
• Methimazole has been used in Pharmacokinetics studies in the laboratory
Chemical Identifiers
| 60-56-0 | |
| 114.17 | |
| PMRYVIKBURPHAH-UHFFFAOYSA-N | |
| 1349907 | |
| 3-methyl-1H-imidazole-2-thione |
| C4H6N2S | |
| MFCD00179321 | |
| methimazole, thiamazole, 2-mercapto-1-methylimidazole, tapazole, mercazolyl, 1-methylimidazole-2-thiol, mercazole, metazolo, methimazol, thiamazol | |
| CHEBI:50673 | |
| CN1C=CNC1=S |
Specifications
| 60-56-0 | |
| Cream to White | |
| >100°C | |
| Authentic | |
| C4H6N2S | |
| 24,17 | |
| methimazole, thiamazole, 2-mercapto-1-methylimidazole, tapazole, mercazolyl, 1-methylimidazole-2-thiol, mercazole, metazolo, methimazol, thiamazol | |
| PMRYVIKBURPHAH-UHFFFAOYSA-N | |
| 3-methyl-1H-imidazole-2-thione | |
| 1349907 | |
| 114.16 | |
| Crystalline Powder |
| 140.0°C to 145.0°C | |
| 280.0°C | |
| 1% (105°C, 2 hrs) max. | |
| 98% | |
| MFCD00179321 | |
| 15,6043 | |
| Solubility in water: soluble. Other solubilities: soluble in ethanol and acetone,sparingly soluble in ether,petr. ether,benzene | |
| CN1C=CNC1=S | |
| 114.17 | |
| CHEBI:50673 | |
| 98% | |
| 2-Mercapto-1-methylimidazole |
Safety and Handling
GHS H Statement
May cause an allergic skin reaction.
Suspected of damaging fertility.
Suspected of damaging the unborn child.
GHS P Statement
Wear eye protection/face protection.
Use personal protective equipment as required.
Avoid breathing dust/fume/gas/mist/vapors/spray.
Contaminated work clothing should not be allowed out of the workplace.
GHS Signal Word: Warning
missing translation for 'einecsNumber' : 200-482-4
Product Identifier
Signal Word
Hazard Category
Hazard Statement
Precautionary Statement
- 2-Mercapto-1-methylimidazole
Signal Word
- Warning
Hazard Category
- Reproductive toxicity Category 2
- Respiratory sensitiser Category 1
Hazard Statement
- H361fd-Suspected of damaging fertility. Suspected of damaging the unborn child.
- H317-May cause an allergic skin reaction.
Precautionary Statement
- P261-Avoid breathing dust/fume/gas/mist/vapours/spray.
- P272-Contaminated work clothing should not be allowed out of the workplace.
- P280-Wear protective gloves/protective clothing/eye protection/face protection.
RUO – Research Use Only