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5-Azacytidine, Tocris Bioscience™

Product Code. 18083992
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Quantity:
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

DNA methyltransferase inhibitor

DNA methyltransferase inhibitor. Incorporates into DNA forming covalent adducts with cellular DNMT1, depleting enzyme activity. Induces demethylation and reactivation of silenced genes. Improves the efficiency of reprogramming of stem cells; induces differentiation of mesenchymal stem cells into cardiomyocytes.

Specifications

CAS 320-67-2
Molecular Formula C8H12N4O5
Quantity 50 mg
Synonym 5-azacytidine, azacitidine, ladakamycin, azacytidine, vidaza, mylosar, azacitidina, azacitidinum, 5-azacitidine, azacitidinum inn-latin
InChI Key NMUSYJAQQFHJEW-KVTDHHQDSA-N
SMILES NC1=NC(=O)N(C=N1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O
IUPAC Name 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydro-1,3,5-triazin-2-one
Molecular Weight (g/mol) 244.21
PubChem CID 9444
ChEBI CHEBI:2038
Formula Weight 244.2
Percent Purity >98%
Chemical Name or Material 5-Azacytidine
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