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8-CPT-2Me-cAMP, sodium salt, Tocris Bioscience™

Product Code. 18004682
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Quantity:
1 mg
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Description

Selective Epac activator

Selective activator of Epac, the cAMP-sensitive guanine nucleotide-exchange factor for Rap1 and Rap2. Activates Epac1 (EC50 = 2.2 μM), but not PKA (EC50 > 10 μM). Stimulates Epac-mediated Ca2+-mediated Ca2+ release in pancreatic β-cells in vitro. Cell permeable analog (Cat. No. 4853) also available.

Specifications

CAS 634207-53-7
Molecular Formula C17H17ClN5NaO6PS
Quantity 1 mg
Synonym 8-cpt-2me-camp, sodium salt
InChI Key IORFFVUNBNOFAO-KHXPSBENSA-N
SMILES COC1C2C(COP(=O)(O2)O)OC1N3C4=C(C(=NC=N4)N)N=C3SC5=CC=C(C=C5)Cl.[Na]
IUPAC Name 9-[(4aR,6R,7R,7aR)-2-hydroxy-7-methoxy-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl]-8-(4-chlorophenyl)sulfanylpurin-6-amine;sodium
Molecular Weight (g/mol) 508.826
PubChem CID 131856562
Formula Weight 507.82
Percent Purity >99%
Chemical Name or Material EPAC Activators
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