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  8. A 867744, Tocris Bioscience™

A 867744, Tocris Bioscience™

Product Code. 30001532
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Quantity:
10 mg
50 mg
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This item is not returnable. View return policy

Description

Positive allosteric modulator of α7 nAChR

Positive allosteric modulator of α7 nAChRs (IC50 values are 0.98 and 1.12 μM for human and rat α7 receptor ACh-evoked currents respectively, in X. laevis oocytes). Displays no activity at 5-HT3A, α3β4 or α4β2 nAChRs. Brain penetrant.

Chemical Identifiers

CAS 1000279-69-5
Molecular Formula C20H19ClN2O3S
Molecular Weight (g/mol) 402.893
InChI Key ABACVOXFUHDKNZ-UHFFFAOYSA-N
Synonym unii-o6nw23a765, 4-5-4-chlorophenyl-2-methyl-3-propionylpyrrol-1-yl benzenesulfonamide, 4-5-4-chlorophenyl-2-methyl-3-propanoylpyrrol-1-yl benzenesulfonamide, d0da1e, benzenesulfonamide, 4-5-4-chlorophenyl-2-methyl-3-1-oxopropyl-1h-pyrrol-1-yl, 4-5-4-chlorophenyl-2-methyl-3-propionyl-1h-pyrrol-1-yl-benzenesulfonamide, 4-5-4-chloro-phenyl-2-methyl-3-propionyl-pyrrol-1-yl-benzenesulfonamide, 4-5-4-chlorophenyl-2-methyl-3-1-oxopropyl-1h-pyrrol-1-yl benzenesulfonamide, 4-5-4-chlorophenyl-2-methyl-3-propanoyl-1h-pyrrol-1-yl benzene-1-sulfonamide
PubChem CID 23642319
IUPAC Name 4-[5-(4-chlorophenyl)-2-methyl-3-propanoylpyrrol-1-yl]benzenesulfonamide
SMILES CCC(=O)C1=C(N(C(=C1)C2=CC=C(C=C2)Cl)C3=CC=C(C=C3)S(=O)(=O)N)C

Specifications

Quantity 50 mg
Formula Weight 402.89
Percent Purity >97%
Chemical Name or Material A 867744
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