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Thermo Scientific™ Acclaim™ Trinity P1 HPLC Columns

Use these mixed-mode columns for simultaneous separation of pharmaceutical drug substances and their counter ions with high efficiency.

Brand: Thermo Scientific™ 071387

1090.49 EUR valid until 2025-12-31
Use promo code "25339" to get your promotional price.

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Product Code. 11371943

1095.94 EUR / Each

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Estimated Shipment: 13-05-2025
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Description

Simultaneously separate pharmaceutical drug substances and their counterions with high-efficiency Thermo Scientific™ Acclaim™ Trinity P1 LC Columns. A unique trimodal surface chemistry provides concurrent reversed-phase, cation-exchange and anion-exchange functionalities for maximum flexibility in method development. Easily optimize selectivity by adjusting mobile phase buffer concentration, pH and solvent content—either jointly or independently—to accelerate chromatographic separations and increase productivity.

The Acclaim Trinity P1 stationary phase, based on Nanopolymer Silica Hybrid (NSH) technology, consists of high-purity porous, spherical 3μm silica particles, coated with charged nanopolymer beads. The unique surface chemistry includes an inner-pore area modified with an organic layer that provides both reversed-phase and anion-exchange properties. The outer-pore surface, conversely, is modified with cation-exchange functionality for unparalleled chromatographic performance.

Superior Performance for Pharmaceutical Applications

Ideal selectivity for simultaneous separation of Active Pharmaceutical Ingredients (API) and counterions (basic, neutral and acidic analytes)
Effective retention of hydrophilic ionic and ionizable analytes without ion-pairing reagents
Distinctive spatial separation of the anion-exchange and cation-exchange regions
Flexible method development with each retention mechanism controlled independently
Low column bleed; compatible with mass spectrometry (MS), charged aerosol detection (CAD) and evaporative light scattering detectors (ELSD)
Available in 2.1 and 3.0mm diameters and 50, 100 and 150mm lengths

Complement the Acclaim Trinity P1 column with the Acclaim Trinity P2 column to provide a total solution for pharmaceutical counterion analysis by HPLC. Use the Acclaim Trinity P2 column to separate counterions, including monovalent and divalent cations or anions.

About the Family of Acclaim Specialty HPLC Columns
Acclaim specialty columns have been developed, manufactured and tested to meet the separation needs of specific applications. These columns are based on novel and unique chemistries and provide superior resolution with ease of use.

Use tested to guarantee consistent separations
Ideal selectivity for separating specific target analytes
Excellent peak shapes
Performance tested to ensure high quality and reliability for specific chromatographic separations

Specifications

Column Format	Analytical Column
For Use With	ELSD, UV Detector
Max. Pressure	4500 psi (310 bar)
pH	2.5 to 7
Quantity	Each
Temperature	45°C
Product Line	Acclaim
Column Type	Mixed Mode
Phase	Reversed Phase and Ion Exchange
Green Features	Responsibly packaged

Diameter (Metric)	3 mm
Length (Metric)	100 mm
Particle Size	3 μm
Pore Size	300 Å
Surface Area	100 m²/g
Stationary Phase	Reversed Phase/Anion Exchange/Cation Exchange
Packing Material	Spherical, Nanopolymer Hybrid Silica
Endcapped	Proprietary
Type	Analytical Column

Product Suggestions Documents

Documents

Scientific Resources

Application Notes

Application Note: Simultaneous Determination of Amlodipine and Its Counterion Besylate by HPLC File size: 178.4 kB

Application Note: Steviol Glycoside Determination by HPLC with Charged Aerosol and UV Detections Using the Acclaim Trintiy P1 Column File size: 584.8 kB

Application Update: Mogroside V Determination by HPLC with Charged Aerosol and UV Detections File size: 473.8 kB

Application Note: Quantitative Analysis of Nitrogen Mustard Hydrolysis Products as Ethanolamines File size: 1 MB

Posters

Poster: Advances in Universal Detection File size: 554.7 kB

Poster Note: Expanding the Coverage of Metabolome Using Multiple Liquid Chromatography Modes File size: 1.7 MB

Poster: New Approaches for Simultaneous API and Counterion Analysis Using Charged Aerosol Detection File size: 1 MB

Poster: Is HILIC the Best Way for Determination of Active Pharmaceutical Ingredients and Counterions? File size: 755.4 kB

Brochures

Brochure: IonCount Solution: Complete Solution for Pharmaceutical Counterions File size: 2.2 MB

Product Information

Specification Sheets

Specification Sheet: Acclaim Trinity P1 Column - Superior Pharmaceutical and Counterion Separations File size: 578.6 kB

Specification Sheet: Acclaim Trinity P1 Column File size: 580.5 kB

Manuals

Acclaim Trinity P1 Columns Version: FEB.2016 File size: 1.6 MB

Certificates

A lot number is required to show results for certificates. To find your lot number on previous orders use our order status area.

Lot Number

5 results found

Lot Number	Certificate Type	Date	Catalog Number
Lot Number003483	Certificate TypeCertificate of Analysis	Date06/12/2023	Catalog Number071387
Lot Number5	Certificate TypeCertificate of Analysis	Date06/12/2023	Catalog Number071387
Lot Number003165	Certificate TypeCertificate of Analysis	Date06/12/2023	Catalog Number071387
Lot Number003482	Certificate TypeCertificate of Analysis	Date06/12/2023	Catalog Number071387
Lot Number003481	Certificate TypeCertificate of Analysis	Date06/12/2023	Catalog Number071387

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Limited warranty period: Subject to all warranty requirements and exclusions set out in our Terms and Conditions of Sale, this product is warranted from the date we ship the product and for ninety (90) days thereafter. Disclaimer to internal research use restriction: Any restrictions on the purchaser to utilize the product(s) for internal research purposes only does not apply to the product(s) on the web pages associated with this statement.

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