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CD107a Rat anti-Mouse, Brilliant Violet 421, Clone: 1D4B, BD
Rat Monoclonal Antibody
Brand: BD Biosciences 564347
This item is not returnable.
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Description
The 1D4B antibody recognizes CD107a (Lysosome-Associated Membrane Protein 1, LAMP-1), one of the two major glycoproteins in lysosome membranes which are useful markers to distinguish lysosomes from other organelles. Mouse CD107a consists of a 40-kDa core protein which is heavily glycosylated to form heterogeneous mature glycoprotein of 110-140 kDa. It is principally expressed in epithelial cells and macrophages in a variety of organs in normal and Beige mutant mice. Several lines of evidence suggest that cell-surface mouse and human LAMP-1 glycoproteins, the expression of which may correlate with malignant transformation, participate in intercellular adhesion and adhesion to extracellular matrix.
The antibody was conjugated to BD Horizon™ BV421 which is part of the BD Horizon Brilliant™ Violet family of dyes. With an Ex Max of 407-nm and Em Max at 421-nm, BD Horizon BV421 can be excited by the violet laser and detected in the standard Pacific Blue™ filter set (eg, 450/50-nm filter). BD Horizon BV421 conjugates are very bright, often exhibiting a 10 fold improvement in brightness compared to Pacific Blue conjugates.
Specifications
| CD107a | |
| Monoclonal | |
| 0.2mg/mL | |
| LAMP-1; LGP-120; LGP-A; P2B | |
| Rat | |
| Affinity Purified | |
| RUO | |
| Mouse | |
| IgG2a κ |
| Flow Cytometry, Immunocytochemistry | |
| 1D4B | |
| Brilliant Violet 421 | |
| Aqueous buffered solution containing BSA and ≤0.09% sodium azide. | |
| Plasma membrane fraction of mouse embryo NIH 3T3 cell line | |
| 50 μg | |
| Primary | |
| Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |