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CD23 Mouse anti-Human, PE, Clone: 138628, Invitrogen™
Mouse Monoclonal Antibody
Brand: Invitrogen MA523549
This item is not returnable.
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Description
CD23 is a 45 kDa glycoprotein which is present on a subpopulation of freshly isolated peripheral blood and tonsil B cells and strongly expressed on EBV-transformed B lymphoblasts. The CD23 molecule is identical to the low affinity IgE receptor found on B cells. Expression of CD23 has been detected in neoplastic cells from cases of B cell chronic lymphocyctic leukaemia and some cases of centroblastic/centrocytic lymphoma. CD23 is present on a subpopulation of freshly isolated peripheral blood and tonsil B cells and strongly expressed on EBV-transformed B lymphoblasts. Functionally, CD23 is involved in B cell growth and differentiation, and IgE production. Further, CD23 has a soluble form that is a potent mitogenic factor. Diseases associated with CD23 dysfunction include chronic conjunctivitis and chronic lymphocytic leukemia.
Specifications
| CD23 | |
| Monoclonal | |
| PE | |
| FCER2 | |
| CD23, CD23A, CLEC4J, FCE2, IGEBF, BLAST-2, C-type lectin domain family 4, member J, CD23 antigen, fc-epsilon-RII, immunoglobulin E-binding factor, low affinity immunoglobulin epsilon Fc receptor, lymphocyte IgE receptor | |
| Mouse | |
| Protein A/G | |
| RUO | |
| 2208 | |
| 4° C, store in dark, DO NOT FREEZE! | |
| Liquid |
| Flow Cytometry | |
| 138628 | |
| Buffered saline solution with BSA and 0.1% sodium azide | |
| P06734 | |
| FCER2 | |
| Human CD23 | |
| 100 Tests | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 |