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Cardiac Troponin T Monoclonal Antibody (13-11), Invitrogen™
Mouse Monoclonal Antibody
Brand: Invitrogen MA512960
423.70 EUR valid until 2024-12-31
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This item is not returnable.
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Description
MA5-12960 targets Troponin T Cardiac Isoform in IF/ICC, IHC (P), and IM applications and shows reactivity with Avian, Canine, Chicken, Fish, Guinea Pig, Human, mouse, Porcine, Rabbit, and Rat samples. The MA5-12960 immunogen is purified rabbit cardiac troponin T isoform (TnT4R).
Cardiac Troponin T is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Cardiac Troponin T is important in proper muscle function and myofibril formation. In the human heart, four cTnT isoforms are expressed in a developmentally regulated manner. Cardiac Troponin T expression in the human heart is affected by heart failure. Mutations within the Cardiac Troponin T protein have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for the Cardiac Troponin T gene undergo alternative splicing that results in many tissue-specific isoforms.
Specifications
| Cardiac Troponin T | |
| Monoclonal | |
| 0.5 mg/mL | |
| PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2 | |
| P02642, P09741, P45379, P50752, P50753 | |
| TNNT2 | |
| Purified rabbit cardiac troponin T isoform (TnT4R) | |
| 200 μL | |
| Primary | |
| Avian, Canine, Chicken, Fish, Guinea Pig, Human, Mouse, Porcine, Rabbit, Rat | |
| Antibody | |
| IgG1 |
| Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot | |
| 13-11 | |
| Unconjugated | |
| TNNT2 | |
| alternatively spliced; cardiac muscle troponin T; cardiac TnT; cardiac troponin 2; cardiac troponin 2 adult #1 isoform; cardiac troponin 2 adult #2 isoform; cardiac troponin 2 embryonic #1 isoform; cardiac troponin 2 embryonic #2 isoform; cardiac troponin 2, exclusion exon 6 #1 isoform; cardiac troponin 2, exclusion exon 6 #2 isoform; cardiac troponin T; cardiac troponin T form I; cardiac troponin T isoform 1; cardiac troponin T isoform 2; cardiac troponin T isoform I; cardiac troponin T2; cardiomyopathy, dilated 1D (autosomal dominant); cardiomyopathy, hypertrophic 2; CMD1D; CMH2; CMPD2; cTnT; Ctt; CTTG; LVNC6; MGC3889; RATCTTG; RCM3; TNNT2; Tnnt3; Tnt; TnTc; troponin T; Troponin T cardiac; troponin T cardiac isoform; troponin T isoform 1; troponin T isoform 2; troponin T splicing mutant isoform 1; troponin T splicing mutant isoform 2; troponin T type 2 (cardiac); troponin T, cardiac muscle; Troponin T, cardiac muscle isoforms; Troponin T2; troponin T2, cardiac; troponin T2, cardiac type; truncated cardiac troponin T | |
| Mouse | |
| Affinity chromatography | |
| RUO | |
| 100009428, 100379561, 100622450, 21956, 24837, 396433, 403532, 7139 | |
| 4° C | |
| Liquid |