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CBS Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 14787-1-AP-20UL
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Description
Strongly expressed in human liver and pancreas, with weaker expression in heart and brain, the cytoplasmic protein cystathionine b-synthase (CBS) operates in the first step of homocysteine transulfuration. CBS, which belongs to the cysteine synthase/cystathionine b-synthase family of proteins, catalyzes the formation of cystathionine from the thrombogenic amino acid homocysteine using pyridoxal phosphate cofactor. Allosteric activation by adenosyl-methionine regulates CBS activity. Deficiencies in CBS are assoc-iated with homocystinuria, a recessively inherited error in sulfur amino acid metabolism that affects many organs and tissues. Symptoms of homocytinuria include arteriosclerosis, thrombosis, dislocated optic lenses, mental retard-ation and skeletal abnormalities.Specifications
| CBS | |
| Polyclonal | |
| Unconjugated | |
| CBS | |
| Beta thionase, CBS, cystathionine beta synthase, HIP4, Serine sulfhydrase | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 12411, 24250, 875 | |
| -20°C | |
| Liquid |
| Western Blot, Immunocytochemistry, Immunoprecipitation, Immunohistochemistry (Paraffin), Immunofluorescence | |
| 0.31 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| P32232, P35520, Q91WT9 | |
| CBS | |
| CBS Fusion Protein Ag6437 | |
| 20 μL | |
| Primary | |
| Human, Rat, Mouse | |
| Antibody | |
| IgG |
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