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CD11b, Alexa Fluor 700, clone: VIM12, Invitrogen™
Mouse Monoclonal Antibody
Brand: Invitrogen CD11B29
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Description
CD11b is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement coated particles. It is identical to CR3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the RGD peptide in C3b. CD11b is also a receptor for fibrinogen, factor X, and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain. The Mac1 CD11b antigen is present on macrophages, granulocytes, natural killer cells, and blood monocytes. CD11b is expressed on 8% of spleen cells, 44% of bone marrow cells, and less than 1% of thymocytes, and is commonly used as a microglial marker in nervous tissue.
The Alexa Fluor™ 700 dye conjugate provides an excellent spectral match to the common long-wavelength excitation sources, with a high extinction coefficient.
Specifications
| CD11b | |
| Monoclonal | |
| Alexa Fluor 700 | |
| ITGAM | |
| CD11B, CR3A, MAC-1, MAC1A, MGC117044, MO1A, SLEB6, Integrin alpha M | |
| Mouse | |
| Purified | |
| ASR, ASR/IVD | |
| 3684 | |
| Store at 2 - 8 °C. | |
| Liquid |
| Flow Cytometry | |
| VIM12 | |
| PBS with BSA and 0.1% sodium azide | |
| P11215 | |
| ITGAM | |
| Human CD11b (Mac-1) | |
| 0.5 mL | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 |
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