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Cilomilast, MedChemExpress

MedChemExpress Cilomilast (SB-207499) is a potent, selective and orally active inhibitor of Phosphodiesterase 4 (PDE4), with IC50s of ∼100 and 120 nM for LPDE4 and HPDE4, respectively.

Brand:  Medchem Express HY-10790

Encompass_Preferred

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Product Code. 16435126

  • 1420.20 EUR / 100mg

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Description

Description

Cilomilast shows selectivity for PDE4 over PDE1, PDE2, PDE3 and PDE5 (IC50=74, 65, >100, and 83 μM, respectively). Cilomilast has anti-inflammatory and immunomodulatory effects and can be used for thr research of asthma and chronic obstructive pulmonary disease (COPD).
Specifications

Specifications

Cilomilast
White
C20H25NO4
SB-207499
O=C([C@H]1CC[C@@](C#N)(CC1)C2=CC=C(OC)C(OC3CCCC3)=C2)O
343.42
Research
COVID-19-immunoregulation
153259-65-5
Research
100 mg
DMSO : ≥ 100 mg/mL (291.19 mM)
343.42
99.89%
Solid
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