missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Biochemical Reagents
  4. Lipids and Lipid Derivatives
  5. Prenol lipids
  6. Monoterpenoids
  7. DPO-1, Tocris Bioscience™

DPO-1, Tocris Bioscience™

Product Code. 30001329
Click to view available options
Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Blocker of KV1.5 channel and IKur current

Blocker of IKur ultrarapid delayed rectifier potassium current and KV1.5 channels (IC50 = 0.31 μM for rKV1.5). Displays selectivity for inhibition of IKur over Ito (8-fold), IK1, IKr and IKs (20-fold) in native myocytes and selectivity for rat recombinant KV1.5 over KV3.1 (∽ 15-fold). Increases action potential duration in atrial but not ventricular myocytes and prevents atrial arrhythmia.

Chemical Identifiers

CAS 43077-30-1
Molecular Formula C22H29OP
Molecular Weight (g/mol) 340.45
MDL Number MFCD09038567
InChI Key BPCNGVCAHAIZEE-UHFFFAOYNA-N
Synonym dpo-1, neomenthyldiphenylphosphine oxide, +-neomenthyl diphenylphosphine oxide, 1s,2s,5r-5-methyl-2-1-methylethyl cyclohexyl diphenyl-phosphine oxide, diphenyl phosphine oxide-1, dpo-1, needles nmr, 1s,2s,5r-2-isopropyl-5-methylcyclohexyl diphenyl phosphine oxide, 1s,2s,5r-2-isopropyl-5-methylcyclohexyl phenyl phosphoroso benzene, 1s,2s,5r-5-methyl-2-propan-2-yl cyclohexyl oxo diphenyl-lambda∼5∼-phosphane, 1s-1?,2?,5?-5-methyl-2-1-methylethyl cyclohexyl diphenylphosphine oxide
PubChem CID 21678144
IUPAC Name {[5-methyl-2-(propan-2-yl)cyclohexyl](phenyl)phosphoroso}benzene
SMILES CC(C)C1CCC(C)CC1P(=O)(C1=CC=CC=C1)C1=CC=CC=C1

Specifications

Quantity 10 mg
Formula Weight 340.44
Percent Purity >99%
Chemical Name or Material DPO-1
missing translation for 'provideContentCorrection'

missing translation for 'productTitle'

missing translation for 'byClickingSubmit' missing translation for 'privacyPolicy'.