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Ethyl bromoacetate, 98%, Thermo Scientific Chemicals
Description
Ethyl bromoacetate is widely used as an alkylating reagent involved in the Reformatsky reaction to prepare the beta-hydroxy esters by reacting with carbonyl compounds. It is also used for the syntheses of witting reagent, artificial diethylstilbestrol antigen, 3-phenyl-1-naphthol and steroidal thiazolidinone derivatives. It finds applications in the preparation of reversibly photoresponsive coumarin-stabilized polymeric nanoparticles in an aqueous medium which act as a detectable drug carrier.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Ethyl bromoacetate is widely used as an alkylating reagent involved in the Reformatsky reaction to prepare the beta-hydroxy esters by reacting with carbonyl compounds. It is also used for the syntheses of witting reagent, artificial diethylstilbestrol antigen, 3-phenyl-1-naphthol and steroidal thiazolidinone derivatives. It finds applications in the preparation of reversibly photoresponsive coumarin-stabilized polymeric nanoparticles in an aqueous medium which act as a detectable drug carrier.
Solubility
Miscible with ethanol, acetone, benzene and ethyl ether. Immiscible with water.
Notes
It is a lachrymator. Incompatible with strong oxidizing agents.
Specifications
Specifications
| Melting Point | °C to 38°C |
| Density | 1.506 g/mL |
| Boiling Point | 159°C |
| Flash Point | 47°C (117°F) |
| Assay Percent Range | 98% |
| Linear Formula | BrCH2CO2CH2CH3 |
| Refractive Index | 1.451 |
| Quantity | 100 g |
| UN Number | UN1603 |
| Solubility Information | Miscible with ethanol,acetone,benzene and ethyl ether. Immiscible with water. |
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Safety and Handling
- Ethyl bromoacetate
- Danger
- Acute toxicity Category 1
- Acute toxicity Category 2
- Flammable liquid Category 3
- H226-Flammable liquid and vapour.
- H300-Fatal if swallowed.
- H310-Fatal in contact with skin.
- H330-Fatal if inhaled.
- P210-Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
- P280-Wear protective gloves/protective clothing/eye protection/face protection.
- P303+P361+P353-IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
- P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
- P310-Immediately call a POISON CENTER/doctor/.
- P330-Rinse mouth.
- MIXTURE LIST-Contains : Ethyl bromoacetate
RUO – Research Use Only