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Ethyl potassium malonate, 98%, Thermo Scientific Chemicals

Product Code. 11419582
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Quantity:
25 g
100 g
500 g
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Ethyl potassium malonate is used as a competitive inhibitor of the enzyme succinate dehydrogenase. It acts as a precursor to produce (trimethylsilyl)ethyl malonate, which is utilized to prepare beta-ketoesters by acylation. Further, it reacts with aryl nitriles to prepare beta-amino acrylates in the presence of zinc chloride and a catalytic amount of Hünig's base. In addition to this, it serves as an intermediate for the preparation of ethyl tert-butyl malonate.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Ethyl potassium malonate is used as a competitive inhibitor of the enzyme succinate dehydrogenase. It acts as a precursor to produce (trimethylsilyl)ethyl malonate, which is utilized to prepare beta-ketoesters by acylation. Further, it reacts with aryl nitriles to prepare beta-amino acrylates in the presence of zinc chloride and a catalytic amount of Hünig′s base. In addition to this, it serves as an intermediate for the preparation of ethyl tert-butyl malonate.

Solubility
Soluble in water.

Notes
Hygroscopic. Incompatible with strong oxidizing agents.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 6148-64-7
Molecular Formula C5H7KO4
Molecular Weight (g/mol) 170.205
MDL Number MFCD00035603
InChI Key WVUCPRGADMCTBN-UHFFFAOYSA-M
Synonym ethyl potassium malonate, potassium 3-ethoxy-3-oxopropanoate, potassium ethyl malonate, potassium monoethyl malonate, monoethyl malonate potassium salt, malonic acid monoethyl ester potassium salt, monoethyl potassium malonate, ethyl malonate potassium salt, propanedioic acid, monoethyl ester, potassium salt, ethylpotassiummalonate
PubChem CID 3446434
IUPAC Name potassium;3-ethoxy-3-oxopropanoate
SMILES CCOC(=O)CC(=O)[O-].[K+]

Specifications

Melting Point ∼200°C (decomposition)
pH 9.1
Odor Odorless
Linear Formula KO2CCH2CO2CH2CH3
Quantity 100 g
Beilstein 3721682
Sensitivity Hygroscopic
Solubility Information Soluble in water.
Formula Weight 170.21
Percent Purity 98%
Chemical Name or Material Ethyl potassium malonate
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RUO – Research Use Only

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