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Thermo Scientific™ GeneBLAzer™ ENDRB-NFAT-bla HEK 293T Cells

GeneBLAzer™ EDNRB-NFAT-bla HEK293T cells contain the human Endothelin Type B Recpetor (EDNRB) stably integrated into the CellSensor™ NFAT-bla HEK293T cell line.

Brand:  Thermo Scientific™ K1727

Product Code. 10542764

  • 15770.00 EUR / Each
Estimated Shipment: 19-12-2024
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Description

Description

GeneBLAzer™ EDNRB-NFAT-bla HEK293T cells contain the human Endothelin Type B Recpetor (EDNRB) stably integrated into the CellSensor™ NFAT-bla HEK293T cell line. CellSensor™ NFAT-bla HEK293T cells (Cat. No. K1538) contain a beta-lactamase reporter gene under control of the Nuclear Factor of Activated T-cells (NFAT) response element.

The GeneBLAzer™ EDNRB-NFAT-bla HEK293T cells are functionally validated for Z' and EC50 concentrations of ET-1. In addition, GeneBLAzer™ EDNRB-NFAT-bla HEK293T cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary.

The ENDRB receptor mediates signaling of endothelin proteins that regulate several critical biological processes, including the development and function of blood vessels, the production of certain hormones, and the stimulation of cell growth and division. Defects in EDNRB mediated signaling have been implicated in a wide range of diseases, including cancer, hypertension and cardiovascular disorders.

For Academic pricing please login or contact us at discoverysciences@invitrogen.com.

TRUSTED_SUSTAINABILITY
Specifications

Specifications

NM_000115.1
Dividing Cells
Fluorescence
EDNRB
Single Cell Clone Origin
2 x 106 Cells
EDNRB
293T (HEK)
GPCR
Cell-based beta lactamase reporter gene
LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol.

Includes:
• GeneBLAzer™ EDNRB-NFAT-bla HEK293T cells
• GeneBLAzer™ EDNRB-NFAT-bla HEK293T Assay Protocol
• Certificate of Analysis

The GeneBLAzer™ GeneBLAzer™ EDNRB-NFAT-bla HEK293T cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.
FRET
EDNRB-NFAT-bla HEK293T cells, EDNRB-NFAT-bla HEK293T Assay Protocol, Certificate of Analysis
GeneBLAzer™
BLA (Beta-Lactamase)
Cell Line
GeneBLAzer™
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For Research Use Only. Not for use in diagnostic procedures.