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Thermo Scientific™ GeneBLAzer™ RARβ-UAS-bla HEK 293T Cells

RAR beta-UAS-bla HEK 293T cells contain the ligand-binding domain (LBD) of the human retinoic acid receptor beta (RAR beta) fused to the DNA-binding domain of GAL4 stably integrated in the GeneBLAzer™UAS-bla HEK 293T cell line.

Brand:  Thermo Scientific™ K1695

Product Code. 10063533

  • 10380.00 EUR / Each
Estimated Shipment: 20-01-2025
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Description

Description

RAR beta-UAS-bla HEK 293T cells contain the ligand-binding domain (LBD) of the human retinoic acid receptor beta (RAR beta) fused to the DNA-binding domain of GAL4 stably integrated in the GeneBLAzer™UAS-bla HEK 293T cell line. GeneBLAzer™UAS-bla HEK 293T cells stably express a beta-lactamase reporter gene under the transcriptional control of an upstream activator sequence (UAS). When an agonist binds to the LBD of the GAL4 (DBD)-RAR beta (LBD) fusion protein, the protein binds to the UAS, resulting in expression of beta-lactamase. RAR beta-UAS-bla HEK 293T cells are functionally validated for Z' and EC50 concentrations of all-trans retinoic acid (ATRA). In addition, RAR beta-UAS-bla HEK 293T cells have been tested for assay performance under variable conditions, including DMSO concentration, cell number, and stimulation time.

TRUSTED_SUSTAINABILITY
Specifications

Specifications

Docosahexaenoic Acid, Phytanic Acid, All-trans-retinoic acid
Cell-based beta lactamase reporter gene
GeneBLAzer™ Nuclear Receptor Cell Lines are shipped on dry ice. Store in liquid nitrogen immediately upon receipt, or thaw for immediate use., Store in liquid nitrogen immediately upon receipt, or thaw for immediate use
Primary Agonist: 9-cis-retinoic acid
Nuclear Receptors
9-cis-retinoic acid
2 x 106 Cells
BLA (Beta-Lactamase)
Dividing Cells
none
Dividing Cells
Fluorescence, Fluorescent
Nuclear Receptors
2 x 106
GeneBLAzer™
HEK 293T Cells
RAR beta, NR1B2, RARB
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For Research Use Only. Not for use in diagnostic procedures.