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  8. GSK2636771, MedChemExpress

GSK2636771, MedChemExpress

Product Code. p-200097983
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Product Code. 16498977

Brand: Medchem Express HY15245

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Description

MedChemExpress GSK2636771 is a potent, selective and orally bioavailable inhibitor of PI3Kβ with a Ki of 0.89 nM and an IC50 of 5.2 nM, showing 900-fold selectivity over p110α and p110γ, and 10-fold selectivity over p110δ isoforms.

GSK2636771 is a potent, selective and orally bioavailable inhibitor of PI3Kβ with a Ki of 0.89 nM and an IC50 of 5.2 nM, showing 900-fold selectivity over p110α and p110γ, and 10-fold selectivity over p110δ isoforms.

Specifications

Chemical Name or Material GSK2636771
CAS 1372540-25-4
Color Yellow
Purity Grade Notes Research
Molecular Formula C22H22F3N3O3
Quantity 5 mg
Solubility Information DMSO : 25 mg/mL (57.68 mM; Need ultrasonic)
SMILES CC1=NC2=C(C(O)=O)C=C(C=C2N1CC3=CC=CC(C(F)(F)F)=C3C)N4CCOCC4
Molecular Weight (g/mol) 433.42
Formula Weight 433.42
Percent Purity 98.95%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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