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Invitrogen™ Human TMEM110 (aa 213-252) Control Fragment Recombinant Protein
Recombinant Protein
Brand: Invitrogen™ RP101617
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Description
Acts as a regulator of store-operated Ca(2+) entry (SOCE) at junctional sites that connect the endoplasmic reticulum (ER) and plasma membrane (PM), called ER-plasma membrane (ER-PM) junction or cortical ER (PubMed:26322679, PubMed:26644574). SOCE is a Ca(2+) influx following depletion of intracellular Ca(2+) stores (PubMed:26322679). Acts by interacting with STIM1, promoting STIM1 conformational switch (PubMed:26322679). Involved in STIM1 relocalization to ER-PM junctions (PubMed:26644574). Contributes to the maintenance and reorganization of store-dependent ER-PM junctions (PubMed:26644574). [UniProt]Specifications
Q86TL2 | |
Blocking Assay, Control | |
375346 | |
100 μL | |
RUO | |
STIMATE | |
Human | |
VDNFLMRKGKTKAKLEERGANQDSRNGSKVRYRRAASHEE | |
Liquid |
≥5.0 mg/mL | |
1M urea, PBS with no preservative; pH 7.4 | |
TMEM110 | |
-20° C, Avoid Freeze/Thaw Cycles | |
1810038N08Rik; 2310014H19Rik; AW554125; STIM-activating enhancer; STIM-activating enhancer encoded by TMEM110; STIMATE; Store-operated calcium entry regulator STIMATE; Tmem110; Transmembrane protein 110 | |
Unconjugated | |
Recombinant | |
E. coli |
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