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(R)-PFI 2 hydrochloride, Tocris Bioscience™

Product Code. 30002024
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10mg
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This item is not returnable. View return policy

Description

Potent and selective SETD7 inhibitor

Potent and selective SETD7 histone lysine methyltransferase inhibitor (IC50 = 2 nM). Exhibits >1000-fold selectivity over DNMT1 and a panel of 18 other methyltransferases. Inhibits YAP nuclear translocation and function following activation of the Hippo signaling pathway in MCF7 cells.

Negative Control also available.

Specifications

Molecular Formula C23H25F4N3O3S·HCl
Quantity 10 mg
Synonym (1R)-1-[[3-(Trifluoromethyl)phenyl]methyl]-2-oxo-2-(1-pyrrolidinyl)ethyl]1,2,3,4-tetrahydro-6-isoquinolinesulfonamide hydrochloride
Formula Weight 535.98
Chemical Name or Material 8-Fluoro-1,2,3,4-tetrahydro-N-[(1R)-2-oxo-2-(1-pyrrolidinyl)-1-[[3-(trifluoromethyl)phenyl]methyl]ethyl]-6-isoquinolinesulfonamide hydrochloride
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