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JZP 361, >99%, Tocris Bioscience™

Potent and selective reversible MAGL inhibitor

102.00 EUR - 383.00 EUR

Specifications

Chemical Name or Material [4-(8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinyl](1H-1,2,4-
CAS 1680193-80-9
Purity Grade Notes >99%
Linear Formula C22H20ClN5O
Solubility Information Soluble to 100mM in DMSO and to 20mM in ethanol
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Product Code Brand Quantity Price Quantity & Availability  
30000795
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Tocris Bioscience
5851/10
10 mg
102.00 EUR
10mg
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30000842
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Tocris Bioscience
5851/50
50 mg
383.00 EUR
50mg
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Description

Description

Potent and selective reversible MAGL inhibitor (IC50 = 46 nM). Exhibits 35-fold and 150-fold higher selectivity over human FAAH and ABHD6, respectively (IC50 values are 1.79 and 7.24 μM, respectively). Displays affinity for H1 receptors (pA2 = 6.81). Exhibits no activity at cannabinoid receptors at 10 μM.
Specifications

Specifications

[4-(8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinyl](1H-1,2,4-
>99%
Soluble to 100mM in DMSO and to 20mM in ethanol
1680193-80-9
C22H20ClN5O
405.88
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Safety and Handling

Safety and Handling

Recommended Storage : Store at 4deg;C

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