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  5. Tocris Bioscience™ JZP 361, >99%

Tocris Bioscience™ JZP 361, >99%
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Product Code. p-7121260
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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
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Product Code. 30000795

Brand: Tocris Bioscience™ 5851/10

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Description

Potent and selective reversible MAGL inhibitor

Potent and selective reversible MAGL inhibitor (IC50 = 46 nM). Exhibits 35-fold and 150-fold higher selectivity over human FAAH and ABHD6, respectively (IC50 values are 1.79 and 7.24 μM, respectively). Displays affinity for H1 receptors (pA2 = 6.81). Exhibits no activity at cannabinoid receptors at 10 μM.
TRUSTED_SUSTAINABILITY

Specifications

Chemical Name or Material [4-(8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinyl](1H-1,2,4-
CAS 1680193-80-9
Quantity 10 mg
Solubility Soluble to 100mM in DMSO and to 20mM in ethanol
Molecular Formula C22H20ClN5O
Formula Weight 405.88
Purity >99%
Molecular Weight (g/mol) 405.886
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