missing translation for 'onlineSavingsMsg'
Learn More
Learn More
LE 135, Tocris Bioscience™
Click to view available options
Quantity:
10 mg
50 mg
Description
Retinoic acid antagonist; displays moderate selectivity for RARβ over RARα (Ki values are 0.22 and 1.4 μM respectively). Highly selective over RARγ and RXRα. Inhibits human HL-60 leukemia cell differentiation induced by Am80 (IC50 = 150 nM).
Specifications
Specifications
| Quantity | 10 mg |
| Synonym | chembl37708, 4-5,7,7,10,10-pentamethyl-8,9-dihydronaphtho 2,3-b 1, 4 benzodiazepin-13-yl benzoic acid, 4-5,7,7,10,10-pentamethyl-7,8,9,10-tetrahydro-5h-benzo e naphtho 2,3-b 1,4 diazepin-13-yl benzoic acid, d0x5wp, 4-7,8,9,10-tetrahydro-5,7,7,10,10-pentamethyl-5h-benzo e naphtho 2,3-b 1,4 diazepin-13-yl benzoic acid, 4-5,7,7,10,10-pentamethyl-7,8,9,10-tetrahydro-5 h-5,12-diaza-benzo 4,5 cyclohepta 1,2-b naphthalen-13-yl-benzoic acid, 4-5,7,7,10,10-pentamethyl-7,8,9,10-tetrahydro-5 h-5,12-diaza-benzo 4,5 cyclohepta 1,2-b naphthalen-13-yl-benzoic acid |
| SMILES | CN1C2=CC=CC=C2C(=NC2=C1C=C1C(=C2)C(C)(C)CCC1(C)C)C1=CC=C(C=C1)C(O)=O |
| IUPAC Name | 4-{2,14,14,17,17-pentamethyl-2,10-diazatetracyclo[9.8.0.0³,⁸.0¹³,¹⁸]nonadeca-1(11),3,5,7,9,12,18-heptaen-9-yl}benzoic acid |
| Molecular Weight (g/mol) | 438.57 |
| Formula Weight | 438.56 |
| Percent Purity | >97% |
| Chemical Name or Material | LE 135 |
missing translation for 'provideContentCorrection'
missing translation for 'productTitle'