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Invitrogen™ LIGHT/TNFSF14 Human ELISA Kit
Sandwich ELISA Kit
Brand: Invitrogen™ EHTNFSF14X10
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Description
Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF (tumor necrosis factor) and Fas ligand of the TNF family through their death domain containing receptors, TNFR1 (tumor necrosis factor receptor 1) and Fas. Cell death signals are transduced by death domain (DD)-containing adapter molecules and members of the ICE (interleukin-1-beta converting enzyme)/CED-3 (C. elegans death receptor-3) protease family. A novel DD-containing molecule was recently cloned from mouse, human and monkey and designated Daxx (death associated protein 6). Daxx binds specifically to the Fas death domain and enhances Fas induced apoptosis and activates the Jun N-terminal kinase (JNK) pathway. Daxx is widely expressed in fetal and adult human and mouse tissues indicating its important function in Fas signaling pathways.
Specifications
| O43557 | |
| 15 pg/mL | |
| ELISA | |
| Colorimetric Microplate Reader | |
| TNFSF14 | |
| <10% | |
| HRP | |
| RUO | |
| 2°C to 8°C | |
| 1 hr 20 min |
| 8.23 to 6000 pg/mL | |
| Biotin | |
| Plasma, Serum, Supernatant | |
| 8740 | |
| <12% | |
| Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers | |
| 10 x 96 Tests | |
| Plasma, 50 μL|Serum, 50 μL|Supernatant, 100 μL | |
| LIGHT | |
| 4 hr 45 min |
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