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Invitrogen™ MARK1 Polyclonal Antibody
GREENER_CHOICE

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5110740

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Product Code. 17158663

  • 618.00 EUR / 100µL

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Description

Description

Immunogen sequence: QEEEELKPYT EPDPDFNDTK RIDIMVTMGF ARDEINDALI NQKYDEVMAT YILLGRKPPE FEGGESLSSG NLCQRSRPSS DLNNSTLQSP AHLKVQRSIS ANQKQRRFSD HAGPSIPPAV SYTKRPQANS VESEQK Highest antigen sequence indentity to the following orthologs: Mouse - 93%, Rat - 94%.

MARK1 (MARK) is a serine/threonine kinase which is involved in cytoskeletal organization and biogenesis. Involved in cell polarity by phosphorylating the microtubule-associated proteins MAP2, MAP4 and MAPT/TAU at KXGS motifs, causing detachment from microtubules, and their disassembly. MARK1 is involved in the regulation of neuronal migration through its dual activities in regulating cellular polarity and microtubule dynamics, possibly by phosphorylating and regulating DCX. Also acts as a positive regulator of the Wnt signaling pathway, probably by mediating phosphorylation of dishevelled proteins (DVL1, DVL2 and/or DVL3).
TRUSTED_SUSTAINABILITY
Specifications

Specifications

MARK1
Polyclonal
Unconjugated
MARK1
AW491150; B930025N23Rik; ELKL motif serine/threonine-protein kinase 3; ELKL motif serine-threonine protein kinase 3; Emk3; KIAA1477; MAP/microtubule affinity regulating kinase 1; MAP/microtubule affinity-regulating kinase 1; MARK; MARK1; mark1 {ECO:0000312; microtubule affinity regulating kinase 1; mKIAA1477; mPar-1c; PAR1 homolog c; Par1c; Par-1c; RGD:619882}; serine/threonine-protein kinase MARK1
Rabbit
Antigen affinity chromatography
RUO
4139
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Immunohistochemistry (Paraffin)
0.1 mg/mL
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Q9P0L2
MARK1
Recombinant Protein corresonding to Human MARK1. Recombinant protein control fragment (Product #RP-89777).
100 μL
Primary
Human
Antibody
IgG
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