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Gibco™ Mouse LIGHT, Animal-Free Recombinant Protein, PeproTech®
Recombinant Protein
100.00 EUR - 1147.00 EUR
Specifications
| Accession Number | Q9QYH9 |
|---|---|
| For Use With (Application) | Functional Assay |
| Format | Lyophilized |
| Formulation | protein with no preservative |
| Gene ID (Entrez) | 50930 |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
17866408
|
Gibco™
AF-315-12-250UG |
250 μg |
1147.00 EUR
250µg |
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|
17817078
|
Gibco™
AF-315-12-5UG |
5 μg |
100.00 EUR
5µg |
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Description
Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF (tumor necrosis factor) and Fas ligand of the TNF family through their death domain containing receptors, TNFR1 (tumor necrosis factor receptor 1) and Fas. Cell death signals are transduced by death domain (DD)-containing adapter molecules and members of the ICE (interleukin-1-beta converting enzyme)/CED-3 (C. elegans death receptor-3) protease family. A novel DD-containing molecule was recently cloned from mouse, human and monkey and designated Daxx (death associated protein 6). Daxx binds specifically to the Fas death domain and enhances Fas induced apoptosis and activates the Jun N-terminal kinase (JNK) pathway. Daxx is widely expressed in fetal and adult human and mouse tissues indicating its important function in Fas signaling pathways.Specifications
| Q9QYH9 | |
| Lyophilized | |
| 50930 | |
| TNFSF14 | |
| -20°C | |
| <0.1 EU/ μg | |
| TNFSF14 | |
| Mouse | |
| Recombinant | |
| E. coli |
| Functional Assay | |
| protein with no preservative | |
| 20.1 kDa | |
| HPLC, SDS-PAGE | |
| RUO | |
| CD258; Herpes virus entry mediator ligand; herpesvirus entry mediator ligand; HVEML; HVEM-L; Light; LTg; Ly113; sCD258; sLIGHT; soluble CD258; soluble LIGHT; Tnfsf14; TR2; tumor necrosis factor (ligand) superfamily, member 14; tumor necrosis factor ligand 1 D; tumor necrosis factor ligand superfamily member 14; Tumor necrosis factor ligand superfamily member 14, membrane form; Tumor necrosis factor ligand superfamily member 14, soluble form; tumor necrosis factor superfamily member 14; UNQ391/PRO726 | |
| Protein | |
| Unconjugated | |
| MRLHQRLGDI VAHLPDGGKG SWEKLIQDQR SHQANPAAHL TGANASLIGI GGPLLWETRL GLAFLRGLTY HDGALVTMEP GYYYVYSKVQ LSGVGCPQGL ANGLPITHGL YKRTSRYPKE LELLVSRRSP CGRANSSRVW WDSSFLGGVV HLEAGEEVVV RVPGNRLVRP RDGTRSYFGA FMV | |
| ≥ 98% by SDS-PAGE gel and HPLC analyses. |
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