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Invitrogen™ MUC5AC Monoclonal Antibody (58M1)

Mouse Monoclonal Antibody

Brand: Invitrogen™ MA135707

Product Code. 11545012

510.00 EUR / 100µg

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Description

58M1 recognizes the peptide core of gastric mucin M1 (now: MUC5AC), and more specifically with the e epitope amongst the a, b, c, d, e, f, g and h protein core epitopes defined by Bara for M1. MUC5AC is present in primary ovarian mucinous cancer and gastric cancer, but usually absent in colorectal adenocarcinoma, thus showing an expression pattern opposite to MUC2. Anti-MUC5AC may be useful for differential identification of primary mucinous ovarian tumors from colon adenocarcinoma metastatic to the ovary. MUC5AC antibodies may also be useful for identification pancreatic carcinoma and pre-cancerous changes vs. normal pancreas.

The antibody 2-25LE reacts with Lewisb blood group antigen, a carbohydrate determinant carried on both glycolipids and glycoproteins, detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals.

Specifications

Antigen	MUC5AC
Classification	Monoclonal
Concentration	0.1 mg/mL
Formulation	PBS with 0.02% sodium azide
Gene Accession No.	P98088
Gene Symbols	MUC5AC
Immunogen	Mucin isolated from an ovarian cyst fluid.
Quantity	100 μg
Primary or Secondary	Primary
Target Species	Human, Mouse, Monkey, Bovine, Feline
Product Type	Antibody
Isotype	IgG1

Applications	Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Clone	58M1
Conjugate	Unconjugated
Gene	MUC5AC
Gene Alias	2210005L13Rik; gastric mucin; LeB; lewis B blood group antigen; LOW QUALITY PROTEIN: mucin-5AC; major airway glycoprotein; MGM; MUC5; MUC5AC; MUC-5AC; mucin; mucin 5, subtypes A and C; mucin 5, subtypes A and C, tracheobronchial/gastric; mucin 5ac; mucin 5AC, oligomeric mucus/gel-forming; mucin 5AC, oligomeric mucus/gel-forming pseudogene; mucin-5 subtype AC, tracheobronchial; Mucin-5AC; TBM; Tracheobronchial mucin
Host Species	Mouse
Purification Method	Purified
Regulatory Status	RUO
Gene ID (Entrez)	100847395, 105261014, 17833, 4586
Content And Storage	4°C
Form	Liquid

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Invitrogen™ MUC5AC Monoclonal Antibody (58M1)

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