missing translation for 'onlineSavingsMsg'
Learn More

N,O-Bis(trimethylsilyl)acetamide, 95%, Thermo Scientific Chemicals

Product Code. 11352695
Click to view available options
Quantity:
5 g
25 g
100 g
This item is not returnable. View return policy
This item is not returnable. View return policy

N,O-Bis(trimethylsilyl)acetamide is used as a regioselective desulfation reagent as well as a preparatory agent for carbohydrate and alcohol trimethylsilyl ethers. It is also used for the derivatization of polar functional groups such as carboxylic acids, phenols, steroids, amines, alcohols, alkaloids and amides. It is employed in the formation of stable trimethylsilyl derivatives. Further, it is used in analytical chemistry for the derivatization of compounds in analysis to increase their volatility and to introduce the trimethylsilyl protecting group in organic synthesis. In addition to this, it is used in the protection of hydroxyl groups in natural products, functional groups in organic intermediates and derivatization reagent for gas chromatography-Mass spectral analysis of phenolic acids in fruits.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
N,O-Bis(trimethylsilyl)acetamide is used as a regioselective desulfation reagent as well as a preparatory agent for carbohydrate and alcohol trimethylsilyl ethers. It is also used for the derivatization of polar functional groups such as carboxylic acids, phenols, steroids, amines, alcohols, alkaloids and amides. It is employed in the formation of stable trimethylsilyl derivatives. Further, it is used in analytical chemistry for the derivatization of compounds in analysis to increase their volatility and to introduce the trimethylsilyl protecting group in organic synthesis. In addition to this, it is used in the protection of hydroxyl groups in natural products, functional groups in organic intermediates and derivatization reagent for gas chromatography-Mass spectral analysis of phenolic acids in fruits.

Solubility
Miscible with many nonpolar and polar aprotic solvents.

Notes
Air and moisture sensitive. Incompatible with strong oxidizing agents, water and acids.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 10416-59-8
Molecular Formula C8H21NOSi2
Molecular Weight (g/mol) 203.43
MDL Number MFCD00008270
InChI Key SIOVKLKJSOKLIF-UHFFFAOYSA-N
Synonym n,o-bis trimethylsilyl acetamide, trimethylsilyl 1z-n-trimethylsilylethanimidate
PubChem CID 6913588
SMILES CC(O[Si](C)(C)C)=N[Si](C)(C)C

Specifications

Boiling Point 71°C to 73°C (35mmHg)
Melting Point -24°C
Quantity 25 g
UN Number UN2920
Beilstein 1306669
Flash Point 42°C (107°F)
Solubility Information Miscible with many nonpolar and polar aprotic solvents.
IUPAC Name trimethylsilyl N-(trimethylsilyl)ethanimidate
Formula Weight 203.43
Percent Purity 95%
Refractive Index 1.417
Sensitivity Moisture sensitive
Density 0.829
Chemical Name or Material N,O-Bis(trimethylsilyl)acetamide
Show More Show Less

RUO – Research Use Only

missing translation for 'provideContentCorrection'

missing translation for 'productTitle'