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Tocris Bioscience™ NAV 2729

Selective ARF6 inhibitor

Brand: Tocris Bioscience™ 5986/50

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Product Code. 18755999

1080.00 EUR / 50mg

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Description

NAV 2729 is a selective ARF6 inhibitor (IC50 = 1.0 μM). Selective for ARF6 over other ARF family members and small GTPases. Inhibits ARF6 activation in uveal melanoma cells in vitro and blocks downstream signaling pathways of oncogenic GNAQ. Reduces tumorigenesis in mouse model of uveal melanoma.

Specifications

Color	Yellow
CAS	419547-11-8
Formula Weight	456.88g/mol
Content And Storage	Store at 4°C
Quantity	50 mg

Product Type	Inhibitor
Molecular Formula	C₂₅H₁₇ClN₄O₃
Solubility	Soluble to 100mM in DMSO
For Use With (Application)	Blocks downstream signaling pathways

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Tocris Bioscience™ NAV 2729

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