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NKP-1339, MedChemExpress

Product Code. 16473087
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Product Code. 16473087

Brand: Medchem Express HY16350

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Description

MedChemExpress NKP-1339 (IT-139; KP-1339) is the first-in-class ruthenium-based anticancer agent in development against solid cancer with limited side effects. NKP-1339 induces G2/M cell cycle arrest, blockage of DNA synthesis, and induction of apoptosis via the mitochondrial pathway. NKP-1339 has a high tumor targeting potential, strongly binds to serum proteins such as albumin and transferrin and activates in the reductive tumor milieu.

NKP-1339 (IT-139

Specifications

Chemical Name or Material NKP-1339
Physical Form Solid
CAS 197723-00-5
Color Dark Brown
Quantity 50 mg
Purity Grade Notes Research
Molecular Formula C14H12Cl4N4NaRu
For Use With (Application) Cancer-Kinase/protease
Synonym IT-139 KP-1339
Solubility Information DMSO : ≥ 59 mg/mL (117.50 mM)
SMILES [Cl-][Ru+3]([N]1=CC2=CC=CC=C2N1)([Cl-])([Cl-])([N]3=CC4=CC=CC=C4N3)[Cl-].[Na+]
Molecular Weight (g/mol) 502.14
Formula Weight 502.14
Percent Purity 98.14%
Grade Research
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Research purposes only

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