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Tocris Bioscience™ NSC 23766

Selective inhibitor of Rac1-GEF interaction; antioncogenic

228.00 EUR - 852.00 EUR

Specifications

Product Type NSC 23766
Molecular Weight (g/mol) 530.97
Inhibitors Rho GTPase Inhibitors
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Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
18765346
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Tocris Bioscience™
2161/10 		10 mg
228.00 EUR
10mg
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18014632
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Tocris Bioscience™
2161/50 		50 mg
852.00 EUR
50mg
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Description

Description

Selective inhibitor of Rac1-GEF interaction. Prevents Rac1 activation by Rac-specific guanine nucleotide exchange factors (GEFs) TrioN and Tiam1 (IC50 ∽ 50 μM) without affecting Cdc42 or RhoA activation. Inhibits Rac1-mediated cell functions and is reported to reverse tumor cell phenotypes in prostate cancer cells.
Specifications

Specifications

NSC 23766
530.97
Rho GTPase Inhibitors
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