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Tocris Bioscience™ OXF BD 02

Selective BRD4(1) inhibitor

Brand:  Tocris Bioscience™ 4928/50

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Product Code. 18722459

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Description

Description

OXF BD 02 is a selective inhibitor of the first bromodomain of BRD4 (BRD4(1)) (IC50 = 382 nM). Exhibits 2-3-fold selectivity for BRD4(1) over the CBP bromodomain and has little affinity for a range of other bromodomains. Reduces viability of lung adenocarcinoma cell lines and attenuates proliferation of MV-4-11 leukemia cells. Cell permeable.
Specifications

Specifications

>98%
OXF BD 02
OXF BD 02
50 mg
295.33
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