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Thermo Scientific™ SIA (succinimidyl iodoacetate)

Product Code. 10465944 Shop All Thermo Scientific Products
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Quantity:
50 mg
Unit Size:
50mg
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Product Code. 10465944

Brand: Thermo Scientific™ 22349

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This item is not returnable. View return policy

Description

Crosslink amines to sulfhydryls with this very short crosslinker composed of NHS-ester and iodoacetyl (haloacetyl) groups at ends of a 3-atom (1.5A) spacer arm.

Thermo Scientific™ Pierce SIA is a very short (1.5 Å) crosslinker for amine-to-sulfhydryl conjugation via N-hydroxysuccinimide (NHS) ester and iodoacetyl reactive groups.

Suited to capturing amine and sulfhydryl groups in very close proximity

Highlights:

  • Reactive groups: NHS ester and iodoacetyl
  • Reactive toward: amino and sulfhydryl groups
TRUSTED_SUSTAINABILITY

Specifications

Chemical Reactivity Amine-Sulfhydryl
Cleavable No
Description SIA
Molecular Weight (g/mol) 283.02
PEGylated No
Spacer Arm Length 1.5 Å
Content And Storage Upon receipt store at 4°C protected from moisture.
Cell Permeability Yes
Shipping Condition Ambient
Product Line Pierce
Labeling Method Chemical Labeling
Crosslinker Type Heterobifunctional
Reactive Moiety Haloacetyl, NHS Ester
Spacer Short (<10 Å)
Form Solid
Quantity 50 mg
Solubility DMF, DMSO
Format Standard
Water Soluble No
Product Type Crosslinker
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Safety and Handling

compliance-icons
Product Identifier
  • SIA (succinimidyl iodoacetate)
 Signal Word
  • Warning
 Hazard Category
  • Serious eye damage/eye irritation Category 2
  • Skin corrosion/irritation Category 2
  • Specific target organ toxicity Category 3
 Hazard Statement
  • H315-Causes skin irritation.
  • H319-Causes serious eye irritation.
  • H335-May cause respiratory irritation.
 Precautionary Statement
  • P261-Avoid breathing dust/fume/gas/mist/vapours/spray.
  • P302+P352-IF ON SKIN: Wash with plenty of water/soap.
  • P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
  • P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P332+P313-If skin irritation occurs: Get medical advice/attention.
  • P337+P313-If eye irritation persists: Get medical advice/attention.
 Supplemental information
  • MIXTURE LIST-Contains : N-Hydroxysuccinimidyl iodoacetate

For Research Use Only. Not for use in diagnostic procedures.

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