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Poly-L-Lysine Hydrobromide, MP Biomedicals™
Promotes cell adhesion to solid substrates. Poly-L-Lysine Hydrobromide, MP Biomedicals is a positively charged amino acid polymer. It acts as a nonspecific attachment factor by enhancing electrostatic interactions between negatively charged ions of the ce
Brand: MP Biomedicals 0210269191
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Description
Poly-lysine binds to DNA, red cell membrane and any negatively charged protein. It is typically used as a coating substrate for culture dishes, slides, etc. It enhances electrostatic interactions to promote cell adhesion. With cells that can digest poly-L-lysine, poly-D-lysine should be used as the attachment factor.
- When adsorbed to the culture surface, poly-lysine increases the number of positively charged sites available for cell binding
- When it is absorbed to the cell culture surface, poly-L-lysine functions to increase the number of positively charged sites available for cell binding
Other applications of Poly-L-lysine include:
- Conjugation to methotrexate for increased drug transport
- Microencapsulation of islets
- Use in a simple reproducible procedure for chromosomal preparations from a variety of tissues
- Immobilation of living cells in biocompatible semipermeable microcapsules
- In the preparation of polycationic beads
- Conjugation to albumin and horseradish peroxidase to enhance cellular uptake
Specifications
| 25988-63-0 | |
| White Powder | |
| 1g |
| Store at –20°C | |
| 402.54 |