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PPAPDC2 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Invitrogen PA112769
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Description
A suggested positive control for this product is testislysate.
PPAPDC2 is a phosphatase that dephosphorylates Presqualene diphosphate (PSDP) into presqualene monophosphate (PSMP), suggesting that it may have important role in innate immunity. PSDP is a bioactive lipid that rapidly remodels to PSMP upon cell activation. PPAPDC2 displays diphosphate phosphatase activity with a substrate preference for PSDP > FDP > phosphatidic acid. PPAPDC2 activity is independent of Mg2+ and has been identified in activated human neutrophil (PMN) extracts. It is widely expressed in human tissues. Recent studies shows PPAPDC2 is a functional isoprenoid diphosphate phosphatase.
Specifications
| PPAPDC2 | |
| Polyclonal | |
| PBS with 0.1% BSA and 0.08% sodium azide | |
| Q8IY26 | |
| PLPP6 | |
| Synthetic peptide corresponding to human phosphatidic acid phosphatase type 2 domain containing 2 (PPAPDC2). | |
| 10 Miniblots | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
| Immunoprecipitation, Western Blot | |
| Unconjugated | |
| PLPP6 | |
| 4932443D16Rik; bA6J24.6; FLJ46512; FLJ90191; MGC15483; PDP1; phosphatidic acid phosphatase type 2 domain containing 2; phosphatidic acid phosphatase type 2 domain-containing protein 2; Phospholipid phosphatase 6; PLPP6; polyisoprenoid diphosphate phosphatase type 1; PPAP2 domain-containing protein 2; Ppapdc2; Presqualene diphosphate phosphatase; PSDP; RP11-6J24.2 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 403313 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Liquid |
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