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PPAR gamma Monoclonal Antibody (A3409A), Invitrogen™
Mouse Monoclonal Antibody
Brand: Invitrogen 419300
This item is not returnable.
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Description
This antibody specifically recognizes human PPAR gamma1 and 2 and cross reacts with mouse and rat PPAR gamma1 and 2. This antibody does not recognize human PPAR alpha and delta.
This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described.
Specifications
| PPAR gamma | |
| Monoclonal | |
| 1 mg/mL | |
| physiological saline with 0.1% sodium azide | |
| O88275, P37231, P37238 | |
| PPARG | |
| Baculovirus-expressed recombinant human PPAR-gamma-1 (3-108 aa). | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG2a |
| ChIP Assay, ELISA, Gel Shift, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot | |
| A3409A | |
| Unconjugated | |
| PPARG | |
| CIMT1; GLM1; HUMPPARG; NR1C3; nuclear hormone receptor; nuclear hormone receptor; PPARG; Nuclear receptor subfamily 1 group C member 3; nuclear receptor transcription factor; OTTHUMP00000185032; OTTHUMP00000185036; peroxisome proliferative activated receptor, gamma; peroxisome proliferative activated receptor, gamma-2; peroxisome proliferator; peroxisome proliferator activated receptor; peroxisome proliferator activated receptor gamma; peroxisome proliferator activated receptor gamma 1; peroxisome proliferator activated receptor gamma 2; peroxisome proliferator activated receptor gamma 4; peroxisome proliferator activated receptor gamma-1; peroxisome proliferator activated receptor gamma-2; peroxisome proliferator activatived receptor gamma; peroxisome proliferator activator receptor, gamma; peroxisome proliferator-activated nuclear receptor gamma variant 1; peroxisome proliferator-activated receptor; peroxisome proliferator-activated receptor gamma; peroxisome proliferator-activated r | |
| Mouse | |
| Ammonium sulfate precipitation | |
| RUO | |
| 19016, 25664, 5468 | |
| Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C | |
| Liquid |