missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Chemicals
  4. Organic compounds
  5. Phenylpropanoids and polyketides
  6. Macrolactams
  7. 18094372

PSC 833, Tocris Bioscience™

Product Code. 18094372
Click to view available options
Quantity:
1 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Inhibitor of P-gp-mediated MDR

P-glycoprotein (P-gp) modulator; inhibits P-gp-mediated multidrug-resistance (MDR). Reverses resistance to several cytotoxic drugs including mitoxantrone and doxorubicin (resistance factors are 2.0 and 6.5 respectively) in human MDR cancer cell lines. Non-immunosuppressive analog of cyclosporin A (Cat. No. 1101).

Specifications

CAS 121584-18-7
Molecular Formula C63H111N11O12
MDL Number MFCD00907207
Quantity 1 mg
Synonym valspodar, amdray, sdz psc 833, sdz-psc-833, 3'-keto-bmt 1-val 2-cyclosporin a, unii-q7zp55kf3x, amdray tn, valspodar usan/inn, q7zp55kf3x, sdz-psc 833
InChI Key YJDYDFNKCBANTM-QCWCSKBGSA-N
SMILES C\C=C\C[C@@H](C)C(=O)[C@@H]1N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C(=O)[C@@H](NC1=O)C(C)C)C(C)C
IUPAC Name (3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-1,4,7,10,12,15,19,25,28-nonamethyl-33-[(2R,4E)-2-methylhex-4-enoyl]-6,9,18,24-tetrakis(2-methylpropyl)-3,21,30-tris(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecone
Molecular Weight (g/mol) 1214.65
PubChem CID 5281884
ChEBI CHEBI:8985
Formula Weight 1214.62
Percent Purity >98%
Chemical Name or Material PSC 833
Show More Show Less
Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.