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PSG3 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Invitrogen PA531705
This item is not returnable.
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Description
Recommended positive controls: HCT116. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The pregnancy-specific glycoproteins (PSGs) are a group of closely related secreted glycoproteins that are highly expressed in fetal placental syncytiotrophoblast cells. Members of the PSG protein family share a characteristic N-terminal domain that is homologous to the immunoglobulin variable region. PSGs become detectable in serum during the first two to three weeks of pregnancy and increase as the pregnancy progresses, eventually representing the most abundant fetal protein in the maternal blood at term. PSGs function to stimulate secretion of TH2-type cytokines from monocytes, and they may also modulate the maternal immune system during pregnancy, thereby protecting the semi-allotypic fetus from rejection. Eleven human PSG proteins (PSG1-PSG11) have been described.
Specifications
| PSG3 | |
| Polyclonal | |
| Unconjugated | |
| PSG3 | |
| Carcinoembryonic antigen SG5; pregnancy specific beta-1-glycoprotein 3; pregnancy-specific beta-1-glycoprotein 3; pregnancy-specific glycoprotein 3; PS-beta-G-3; PSBG-3; PSG3; sg5 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 5671 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot | |
| 0.98 mg/mL | |
| 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7 | |
| Q16557 | |
| PSG3 | |
| Recombinant fragment corresponding to a region within amino acids 11 and 347 of Human PSG3 | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |