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R&D Systems™ Recombinant Human FCRN Protein
Extensive quality control produces industry leading bioactivity and lot-to-lot consistency that instills confidence in results and ensures reproducibility. Applications: Bioactivity
Brand: R&D Systems™ 8639-FC-050
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Description
Non-covalently associated with endogenous beta 2-MicroglobulinSpecifications
| P55899 | |
| 2217 | |
| 50 μg | |
| Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70° C as supplied. 1 month, 2 to 8° C under sterile conditions after reconstitution. 3 months, -20 to -70° C under sterile conditions after reconstitution. | |
| alpha-chain, Fc fragment of IgG, receptor, transporter, alpha, FCGRT, FcRn, FcRn alpha chain, FCRNimmunoglobulin receptor, intestinal, heavy chain, IgG Fc fragment receptor transporter alpha chain, IgG receptor FcRn large subunit p51, major histocompatibility complex class I-like Fc receptor, Neonatal Fc receptor, neonatal Fc-receptor for Ig | |
| FCGRT | |
| Unconjugated | |
| Recombinant | |
| >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining |
| Bioactivity | |
| Observed M.W.: 30-36kDa (FCRN), 10kDa ( beta 2 Microglobulin), Theoretical M.W.: 31kDa (FCRN), 10kDa ( beta 2 Microglobulin)kDa | |
| Human embryonic kidney cell,HEK293-derived human FCRN protein Ala24-Ser297,with a C-terminal 6-His tag | |
| <0.10 EU per 1μg of the protein by the LAL method. | |
| FCRN/FCGRT | |
| Measured by its binding ability in a functional ELISA. When Recombinant Human FCRN is immobilized at 2μg/mL (100μL/well), the concentration of biotinylated human IgG that produces 50% of the optimal binding response is approximately 2-10μg/mL. | |
| Human | |
| Human embryonic kidney cell, HEK293-derived Ala24-Ser297, with a C-terminal 6-His tag |
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