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Reelin Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Invitrogen PA565442
This item is not returnable.
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Description
Immunogen sequence: TFCEPYGPREL ITTGLNTTTA SVLQFSIGSG SCRFSYSDPS IIVLYAKNNS ADWIQLEKIR APSNVSTIIH ILYLPEDAKG ENVQFQWKQE NLRVGEVYE Highest antigen sequence identity to the following orthologs - mouse 90%, rat 94%.
Reelin in an extracellular matrix serine protease that plays a role in layering of neurons in the cerebral cortex and cerebellum. Regulates microtubule function in neurons and neuronal migration. Affects migration of sympathetic preganglionic neurons in the spinal cord, where it seems to act as a barrier to neuronal migration. Enzymatic activity is important for the modulation of cell adhesion. Binding to the extracellular domains of lipoprotein receptors VLDLR and LRP8/APOER2 induces tyrosine phosphorylation of DAB1 and modulation of TAU phosphorylation.
Specifications
| Reelin | |
| Polyclonal | |
| Unconjugated | |
| RELN | |
| ETL7; extracellular matrix serine protease; LIS2; PRO1598; Reelen; reeler; Reeler protein; Reelin; RELN; Rl | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 5649 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunocytochemistry | |
| 0.2 mg/mL | |
| PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
| P78509 | |
| RELN | |
| Recombinant Human Reelin | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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