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  8. RP 67580, Tocris Bioscience™

RP 67580, Tocris Bioscience™

Product Code. 30001451
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Quantity:
10 mg
50 mg
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Description

Potent and selective NK1 antagonist

Potent and selective tachykinin NK1 receptor antagonist (Ki values are 2.9 nM and > 10 μM for rat NK1, and rat NK2 and NK3 receptors respectively). Displays higher affinity at rat and mouse than human receptors. Antinociceptive in vivo, possibly partly via inhibition of calcium channels.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 135911-02-3
Molecular Formula C29H30N2O2
Molecular Weight (g/mol) 438.571
InChI Key VWBOQFANCXZMAU-LOSJGSFVSA-N
Synonym unii-49u9m41bgy, 7,7-diphenyl-2-1-imino-2-2-methoxyphenyl ethyl perhydroisoindol-4-one, 4h-isoindol-4-one, octahydro-2-1-imino-2-2-methoxyphenyl ethyl-7,7-diphenyl-, 3ar-cis, 3ar,7ar-octahydro-2-1-imino-2-2-methoxyphenyl ethyl-7,7-diphenyl-4h-isoindol, 4h-isoindol-4-one, octahydro-2-1-imino-2-2-methoxyphenyl ethyl-7,7-diphenyl-, 3ar,7ar, tocris-1635, d08kxe, 3ar,7ar-octahydro-2-1-imino-2-2-methoxyphenyl ethyl-7,7-diphenyl-4h-isoindol-4-one, 3ar,7ar-2-1-imino-2-2-methoxy-phenyl-ethyl-7,7-diphenyl-octahydro-isoindol-4-one, 3ar,7ar-2-1-imino-2-2-methoxyphenyl ethyl-7,7-diphenyl-4-perhydroisoindolone
PubChem CID 107686
IUPAC Name (3aR,7aR)-2-[2-(2-methoxyphenyl)ethanimidoyl]-7,7-diphenyl-1,3,3a,5,6,7a-hexahydroisoindol-4-one
SMILES COC1=CC=CC=C1CC(=N)N2CC3C(C2)C(CCC3=O)(C4=CC=CC=C4)C5=CC=CC=C5

Specifications

Quantity 10 mg
Formula Weight 438.57
Percent Purity >97%
Chemical Name or Material RP 67580
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