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  6. 18789896

SB 203580 hydrochloride, Tocris Bioscience™

Product Code. 18789896
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Quantity:
10 mg
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This item is not returnable. View return policy

Description

Selective inhibitor of p38 MAPK; water-soluble

Water-soluble salt of SB 203580 (Cat. No. 1202). Selective inhibitor of p38 mitogen-activated protein kinase (IC50 values are 50 and 500 nM for SAPK2a/p38 and SAPK2b/p38β2 respectively). Displays 100-500-fold selectivity over LCK, GSK3β and PKBα. Shown to inhibit interleukin-2-induced T cell proliferation, cyclooxygenase-1 and -2, and thromboxane synthase.

Specifications

CAS 869185-85-3
Molecular Formula C21H17ClFN3OS
Quantity 10 mg
Synonym 4-[5-(4-Fluorophenyl)-2-[4-(methylsulphonyl)phenyl]-1H-imidazol-4-yl]pyridine hydrochloride
InChI Key WOSGGXINSLMASH-UHFFFAOYNA-N
Molecular Weight (g/mol) 413.90
Formula Weight 413.89
Percent Purity >98%
Chemical Name or Material SB 203580 hydrochloride
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