missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Chemicals
  4. Organic compounds
  5. Organoheterocyclic compounds
  6. Azoles
  7. Imidazoles
  8. SB 590885, Tocris Bioscience™

SB 590885, Tocris Bioscience™

Product Code. 18056012
Click to view available options
Quantity:
10 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Potent B-Raf inhibitor

Potent B-Raf inhibitor (Kd = 0.3 nM). Selective for B-Raf against 46 other kinases (Ki app values are 0.16 and 1.72 nM for B-Raf and c-Raf respectively). Decreases anchorage-independent growth of melanoma cell lines. Inhibits ERK phosphorylation and proliferation in tumor cells expressing B-RafV600E.

Chemical Identifiers

CAS 405554-55-4
Molecular Formula C27H27N5O2
Molecular Weight (g/mol) 453.55
MDL Number MFCD16038645
InChI Key DPCXEUSDRQOOGZ-UHFFFAOYSA-N
Synonym 5-2-4-2-dimethylamino ethoxy phenyl-5-4-pyridinyl-1h-imidazol-4-yl-2,3-dihydro-1h-inden-1-one oxime, 2-4-4-1e-1-hydroxyimino-2,3-dihydroinden-5-yl-5-pyridin-4-yl-1h-imidazol-2-yl phenoxy ethyl dimethylamine, 2-4-4-1z-1-hydroxyimino-2,3-dihydroinden-5-yl-5-pyridin-4-yl-1h-imidazol-2-yl phenoxy ethyl dimethylamine, 2-4-4-1-hydroxyimino-2,3-dihydroinden-5-yl-5-pyridin-4-yl-1h-imidazol-2-yl phenoxy ethyl dimethylamine
PubChem CID 53239990
IUPAC Name (2-{4-[5-(1,4-dihydropyridin-4-ylidene)-4-(3-nitroso-2,6-dihydro-1H-inden-6-ylidene)-4,5-dihydro-1H-imidazol-2-yl]phenoxy}ethyl)dimethylamine
SMILES CN(C)CCOC1=CC=C(C=C1)C1=NC(C(N1)=C1C=CNC=C1)=C1C=CC2=C(CCC2=C1)N=O

Specifications

Quantity 10 mg
Formula Weight 453.54
Percent Purity >98%
Chemical Name or Material SB 590885
Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.