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Tocris Bioscience™ Spadin
Potent K2P2.1 (TREK-1) channel blocker
Brand: Tocris Bioscience™ 5594/1
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Description
Spadin is a potent TREK-1 channel blocker (IC50 = 71 nM). Enhances dorsal raphe nucleus 5-HT neurotransmission in mice. Induces hippocampal CREB activation and neurogenesis in adult mice. Exhibits antidepressant effects in mouse models of depression. Brain penetrant.Specifications
0.95 | |
2012.34 | |
1 mg |
Spadin | |
Spadin | |
Tyr-Ala-Pro-Leu-Pro-Arg-Trp-Ser-Gly-Pro-Ile-Gly-Val-Ser-Trp-Gly-Leu-Arg |
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