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SQLE Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Invitrogen PA554265
This item is not returnable.
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Description
Immunogen sequence: ELHAPLTVVA DGLFSKFRKS LVSNKVSVSS HFVGFLMKNA PQFKANHAEL ILANPSPVLI YQISSSETRV LVDIRGEMPR NLREYMVEKI YPQIPDHLKE PFLEATDNSH LRSMPASFLP PSSVKKRGVL LLGDA Highest antigen sequence identity to the following orthologs: Mouse - 85%, Rat - 86%.
SQLE, also named as ERG1, SE and SM, belongs to the squalene monooxygenase family. It catalyzes the first oxygenation step in cholesterol synthesis, acting on squalene before cyclization into the basic steroid structure. SQLE may serve as a flux-controlling enzyme beyond 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGR, considered as rate limiting). It is also post translationally regulated by cholesterol-dependent proteasomal degradation. The MW of SQLE is about 64 kDa.
Specifications
| SQLE | |
| Polyclonal | |
| Unconjugated | |
| SQLE | |
| AI323792; Erg1; FLJ30795; SE; Sqle; Squalene epoxidase; squalene monooxygenase; Squalene monooxygenase-like protein | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 6713 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry, Western Blot | |
| 0.2 mg/mL | |
| PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
| Q14534 | |
| SQLE | |
| Recombinant protein corresponding to Human SQLE | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
Research Use Only