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  6. Tetracycline, Thermo Scientific Chemicals

Tetracycline, Thermo Scientific Chemicals

Product Code. 15424259
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Quantity:
25 g

Description

Tetracycline, Deschlorobiomycin, CAS # 60-54-8, is a broad-spectrum napthacene antibiotic that inhibits bacterial growth.

Tetracycline is used for treatment of chronic inflammatory cells. Tetracycline derivatives induce apoptosis in osteoclasts, Jurkat T lymphocyte cells and in cultured monocytes and macrophages. It is a compound that has been shown to induce apoptosis in various cells.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Tetracycline is a semisynthetic compound derived from chlortetracycline, an isolate from Streptomyces aureofaciens
• Tetracycline is a broad-spectrum bacteriostatic that inhibits polypeptide formation by binding the 30S ribosomal subunit and preventing aminoacyl tRNA-mRNA complex formation
• It may have other bactericidal properties such as limited binding to the 50S subunit

Application

• Tetracycline has been shown to exhibit antiprotozoal properties
• It can be used to kill both gram-positive and gram-negative bacteria
• It is suitable for use in laboratory applications in resistance gene testing and research on infection

TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 60-54-8
Molecular Formula C22H24N2O8
Molecular Weight (g/mol) 444.44
MDL Number MFCD00151232
InChI Key JYHCQVWYCGHXGP-BPPSBWQWSA-N
PubChem CID 54675776
SMILES CN(C)[C@H]1[C@@H]2C[C@H]3C(=C(O)C4=C(O)C=CC=C4[C@@]3(C)O)C(=O)[C@]2(O)C(=O)\C(=C(\N)O)C1=O

Specifications

Type Tetracycline
Physical Form Crystalline Powder
Melting Point 172°C to 174°C
Color Yellow
Quantity 25 g
Beilstein 2230417
Merck Index 14,9196
Solubility Information Limited solubility in water; Soluble in 1M HCl with heating.
IUPAC Name (4S,4aS,5aS,6S,12aR)-4-(dimethylamino)-1,6,10,11,12a-pentahydroxy-6-methyl-3,12-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide
Formula Weight 444.43
Chemical Name or Material Tetracycline
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Safety and Handling

compliance-icons
Product Identifier
  • Tetracycline
 Signal Word
  • Warning
 Hazard Category
  • Acute toxicity Category 4
 Hazard Statement
  • H302-Harmful if swallowed.
 Precautionary Statement
  • P264-Wash face, hands and anyexposed skin thoroughly after handling.
  • P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
  • P312-Call a POISON CENTER/doctor/if you feel unwell.
 Supplemental information
  • MIXTURE LIST-Contains : Tetracycline

RUO – Research Use Only

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