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Tetrahydro-4H-pyran-4-one, 98%, Thermo Scientific Chemicals
Description
It is employed in the preparation of 4-methoxytetrahydropyran-4-yl protecting group, synthesis of symmetric tetra substituted methanes. The methyl enol ether is a useful protecting agent for alcohols, e.g. in nucleotide synthesis, with the advantage over 3,4-Dihydro-2H-pyran. It is also employed in a study of the enantioselective alpha-aminoxylation of ketones with nitrosobenzene and L-proline in an ionic liquid. It undergoes condensation reactions in the preparation of dipeptides and spiroimidazolones. It is also employed in wittig reactions for the synthesis of Penicillins and in a ring of vitamin D3
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
It is employed in the preparation of 4-methoxytetrahydropyran-4-yl protecting group, synthesis of symmetric tetra substituted methanes. The methyl enol ether is a useful protecting agent for alcohols, e.g. in nucleotide synthesis, with the advantage over 3,4-Dihydro-2H-pyran. It is also employed in a study of the enantioselective alpha-aminoxylation of ketones with nitrosobenzene and L-proline in an ionic liquid. It undergoes condensation reactions in the preparation of dipeptides and spiroimidazolones. It is also employed in wittig reactions for the synthesis of Penicillins and in a ring of vitamin D3
Solubility
Very soluble in water.
Notes
Store away from strong bases and oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.
Specifications
Specifications
Density | 1.084 |
Boiling Point | 165°C to 167°C |
Flash Point | 62°C (144°F) |
Refractive Index | 1.453 |
Quantity | 1 g |
Beilstein | 106463 |
Solubility Information | Very soluble in water. |
Formula Weight | 100.12 |
Percent Purity | 98% |
Chemical Name or Material | Tetrahydro-4H-pyran-4-one |
Safety and Handling
- Tetrahydro-4H-pyran-4-one
- Warning
- Flammable liquid Category 3
- H226-Flammable liquid and vapour.
- P210-Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
- MIXTURE LIST-Contains : Tetrahydro-4H-pyran-4-one
RUO – Research Use Only
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