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TGF alpha Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA5120044

328.68 EUR valid until 2025-03-21
Use promo code "24111" to get your promotional price.

Product Code. 17751444

  • 493.00 EUR / 100µL

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To receive the discount customers must purchase three of the same product at list price in a single order to receive 33.33% discount. There is no limit to the multiples of 3 that customers can buy. Use promo code ”24111” to get your promotional price

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Description

Description

Positive test controls include: 293T, Jurkat, Mouse lung. The target is usually found in the following locations: Cell membrane, Secreted, Single-pass type I membrane protein, extracellular space. Immunogen sequence: ENSTSPLSDP PVAAAVVSHF NDCPDSHTQF CFHGTCRFLV QEDKPACVCH SGYVGARCEH ADLLAVVAAS QKKQA

TGF-alpha is an EGF-related polypeptide growth factor that signals through the EGF receptor, and stimulates the proliferation of a wide range of epidermal and epithelial cells. It is produced by monocytes, keratinocytes, and various tumor cells. TGF-alpha induces anchorage-independence transformation in cultured cells. Human, murine and rat TGF-alpha are cross-species reactive. TGFalpha (aa 50) is a growth factor with 33% homology to EGF, binds to EGFR, activates tyrosine phosphorylation of the receptor, and stimulates cell proliferation. It plays a role in tumor initiation by inducing the reversible transformed phenotype.
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TGF alpha Polyclonal Antibody, Invitrogen™ > 100 μL; Unconjugated

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