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TGF alpha Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Invitrogen PA5120044
328.68 EUR valid until 2025-03-21
Use promo code "24111" to get your promotional price.
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Description
Positive test controls include: 293T, Jurkat, Mouse lung. The target is usually found in the following locations: Cell membrane, Secreted, Single-pass type I membrane protein, extracellular space. Immunogen sequence: ENSTSPLSDP PVAAAVVSHF NDCPDSHTQF CFHGTCRFLV QEDKPACVCH SGYVGARCEH ADLLAVVAAS QKKQA
TGF-alpha is an EGF-related polypeptide growth factor that signals through the EGF receptor, and stimulates the proliferation of a wide range of epidermal and epithelial cells. It is produced by monocytes, keratinocytes, and various tumor cells. TGF-alpha induces anchorage-independence transformation in cultured cells. Human, murine and rat TGF-alpha are cross-species reactive. TGFalpha (aa 50) is a growth factor with 33% homology to EGF, binds to EGFR, activates tyrosine phosphorylation of the receptor, and stimulates cell proliferation. It plays a role in tumor initiation by inducing the reversible transformed phenotype.
Specifications
| TGF alpha | |
| Polyclonal | |
| Unconjugated | |
| TGFA | |
| EGF-like TGF; ETGF; I79_019067; LOC100009150; Protransforming growth factor alpha; RATTGFAA; TFGA; TGF a; TGF type 1; TGF a; TGFA; TGFAA; TGFalpha; TGF-alpha; TGFa; Transforming growth factor; Transforming growth factor alpha; transforming growth factor, alpha; transforming growth factor-alpha; wa1; wa-1; waved 1 | |
| Rabbit | |
| Affinity Chromatography | |
| RUO | |
| 21802, 7039 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| Western Blot | |
| 0.93 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| P01135, P48030 | |
| TGFA | |
| Recombinant fusion protein containing a sequence corresponding to amino acids 24-98 of human TGFA (NP_001093161.1). | |
| 100 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |
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Product Title
TGF alpha Polyclonal Antibody, Invitrogen™ > 100 μL; Unconjugated
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